N-linked (N-) Glycoproteomics of Urinary Exosomes
نویسندگان
چکیده
منابع مشابه
N-glycoproteomics - an automated workflow approach.
Glycan decorations dictate protein functions and thus have crucial importance in life sciences. Previously glycoprotein analysis was mainly focused on the analysis of the liberated glycans allowing detailed structural, but lacking positional information. Analysis of intact glycopeptides required purified glycoproteins and manual interpretation of spectra. We developed an approach where mixtures...
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MNDO semi-empirical SCF MO calculations are used to study the pyramidal nitrogen atom inversion and configurational equilibria in the title compounds.
متن کاملUrinary Exosomes
Exosomes are nanovesicles of endocytic origin that are secreted into the extracellular space or body fluids when a multivesicular body (MVB) fuses with the cell membrane. Interest in exosomes intensified after their description in antigen-presenting cells and the observation that they can significantly moderate immune responses in vivo. In the past few years, several groups have reported on the...
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Many of the proteins that are translocated into the endoplasmic reticulum are glycosylated with the addition of a 14saccharide core unit (Glc,Man,GlcNAc,) to specific asparagine residues of the nascent polypeptide. Glucose residues are then removed by endoplasmic reticulum-located glucosidases, with diglucosylated and monoglucosylated intermediates being formed. In this study, we used a cell-fr...
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noindent We have two goals in this paper. First, we investigate and construct cofree coalgebras over $n$-representations of quivers, limits and colimits of $n$-representations of quivers, and limits and colimits of coalgebras in the monoidal categories of $n$-representations of quivers. Second, for any given quivers $mathit{Q}_1$,$mathit{Q}_2$,..., $mathit{Q}_n$, we construct a new quiver $math...
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ژورنال
عنوان ژورنال: Molecular & Cellular Proteomics
سال: 2015
ISSN: 1535-9476,1535-9484
DOI: 10.1074/mcp.a114.040345